Veda-K1 2X Oral Capsule

Company: Vedco

Each capsule contains 50 mg of Phytonadione

Description

Vitamin K1 Capsules contain phytonadione with excipients in an artificially colored soft gelatin shell.

ACTIONS:

Vitamin K1 Capsules for oral administration possess the same type and degree of activity as does naturally occurring vitamin K. The primary function of vitamin K is to stimulate the production via the liver of active prothrombin from a precursor protein. The mechanism by which vitamin K promotes formation of prothrombin at the molecular level has not been established.

Veda-K1 2X Oral Capsule Indications

Vitamin K1 Capsules are indicated in dogs and cats to counter hypoprothrombinemia induced by ingestion of coumarin-based compounds, common ingredients of commercial rodenticides, and other drug induced hypoprothrombinemia where it is definitely shown that the result is due to interference with vitamin K metabolism, e.g. salicylates.

NOTE:

Regular determinations of prothrombin time response should be performed to guide in the initial and subsequent administration of Vitamin K1 oral capsules. The dosage should be adjusted accordingly.

CONTRAINDICATION:

Hypersensitivity to any component of this medication.

Warnings

It is recommended that Vitamin K1 oral capsules be used in follow-up therapy only after an administration of Vitamin K1 Injection and hospitalization is no longer required. An immediate coagulant effect should not be expected after administration of phytonadione when administered orally.

Phytonadione will not counteract the anticoagulant action of heparin.

Repeated large doses of Vitamin K1 are not warranted in hepatic disease if the response to the initial therapy is unsatisfactory. Failure to respond to Vitamin K1 may indicate that the condition being treated is inherently unresponsive to Vitamin K1.

Precautions

Protect from light at all times. Temporarily resistance to prothrombin-depressing anticoagulants may result, especially when larger doses of phytonadione are used.

Dosage and Administration

For use in large dogs.

Hypoprothrombinemia (with hemorrhage) - Administer orally at the rate of 2.5-5 mg/kg body weight (1 capsule per each 44 pounds of body weight for lower dosage or 1 capsule per each 22 pounds of body weight for higher dosage) daily as conditions require up to 3 weeks. Frequency and amount of oral administration should be guided by regular determination of prothrombin time.

The smallest effective dose should be sought to minimize the risk of adverse reaction.

Veda-K1 2X Oral Capsule Caution

VEDA-K1 2X capsules are sold only to licensed veterinarians.

How Supplied

VEDA-K1 2X oral capsules are available in bottles of 50 capsules each.

FOR ANIMAL USE ONLY

KEEP OUT OF REACH OF CHILDREN

Manufactured for: VEDCO, INC., St. Joseph, Missouri 64504

CPN: 1094306.1