Nobivac Canine 1-DAPPv+L4 (Canada)

Company: Merck Animal Health

CANINE DISTEMPER-ADENOVIRUS TYPE 2-PARAINFLUENZA-PARVOVIRUS VACCINE Modified Live Virus LEPTOSPIRA CANICOLA-GRIPPOTYPHOSA-ICTEROHAEMORRHAGIAE-POMONA BACTERIN

FOR ANIMAL USE ONLY

IN THE ABSENCE OF A VETERINARIAN-CLIENT-PATIENT RELATIONSHIP, FEDERAL REGULATIONS PROHIBIT THE RELABELING, REPACKAGING, RESALE OR REDISTRIBUTION OF THE INDIVIDUAL CONTENTS OF THIS PACKAGE.

THIMEROSAL FREE

PRODUCT DESCRIPTION: Nobivac^® Canine 1-DAPPv+L₄ vaccine is a combination vaccine that unites the benefits of Nobivac^® Canine 1-DAPPv and Nobivac^® Lepto₄ in one vaccination.

Nobivac Canine 1-DAPPv+L4 Indications

This product has been shown to be effective for vaccination of healthy dogs 8 weeks of age or older against canine distemper virus, canine adenovirus type 1 (hepatitis), canine parainfluenza virus, canine parvovirus, Leptospira canicola, L. icterohaemorrhagiae, L. pomona and L. grippotyphosa. Duration of Immunity has not been established. To review efficacy and safety data, go to productdata.aphis.usda.gov.

This product has also been shown to be effective against mortality and leptospiruria (shedding of Leptospira in the urine) caused by L. canicola, L. icterohaemorrhagiae, L. pomona and L. grippotyphosa. Data indicate the development of corneal opacity is not associated with the use of this product.

Dosage and Administration

Shake the Nobivac Lepto₄ vial and transfer its contents to the Nobivac Canine 1-DAPPv vial aseptically. Mix gently until dissolved. Inject one dose (1 mL) subcutaneously. The initial dose may be given at 8 weeks of age or older. Repeat dose 2 to 4 weeks later. Two doses are required for primary immunization.

The presence of maternal antibodies is known to interfere with the development of active immunity in dogs and additional boosters will be required in most young animals. Historically, annual revaccination has been recommended for this product. The need for this booster has not been established. For more information on revaccination frequency, in general or in the face of maternal antibody, consult your veterinarian or the manufacturer.

Precautions

● Store at 2° - 8°C (35°-46°F).

● Do not freeze.

● Use new, non-chemically sterilized needles and syringes.

● Do not mix with other products, except as specified on the label.

● Inactivate unused contents before disposal.

● In case of human exposure, contact a physician.

Warnings

● Contains gentamicin and amphotericin B as preservatives.

● Vaccinate only healthy, non-parasitized dogs.

● Do not vaccinate pregnant bitches.

● The use of a biological product may produce anaphylaxis and/or other inflammatory immune-mediated hypersensitivity reactions. Antidote: Epinephrine, corticosteroids, and antihistamines may all be indicated depending on the nature and severity of the reaction.

● The age at which maternal antibody for canine parvovirus no longer interferes with the development of active immunity varies according to the bitch’s titer and quantity of colostral antibodies absorbed by the puppy.

Intervet Inc. d/b/a Merck Animal Health

Omaha, NE 68103 USA

VLN 165A/PCN 47K1.20

1 800 224-5318 (USA)

1 866 683-7838 (Canada)

For patent information:

http://www.merck.com/product/patent/home.html

CPN: 1208223.4