Newcastle-Bronchitis Vaccine, B1 Type, B1 Strain, Mass & Conn Types, Live Virus (Canada)

Company: Boehringer Ingelheim Animal Health

Newcastle-Bronchitis Vaccine, B1 Type, B1 Strain, Mass & Conn Types, Live Virus Indications

This product has been shown to be effective for the vaccination of healthy chickens one day of age or 14 days of age or older against Newcastle disease and Infectious bronchitis of the Mass and Conn types. The duration of immunity has not been established. For more information regarding efficacy and safety data, see productdata.aphis.usda.gov.

This vaccine contains the B1 type, B1 strain of Newcastle disease virus and infectious bronchitis of the Massachusetts and Connecticut types.

CAUTION: NEWCASTLE DISEASE CAN CAUSE INFLAMMATION OF THE EYELIDS OF HUMANS, USE CAUTION TO AVOID INFECTING EYES. EYE PROTECTION MUST BE WORN WHEN RECONSTITUTING AND ADMINISTERING THIS VACCINE. AVOID CONTAMINATING HANDS AND CLOTHING WITH THE VACCINE. HAND WASHING IS RECOMMENDED AFTER EXPOSURE TO THE PRODUCT.

Store at 2-8°C (35-46°F). Do not freeze. Do not vaccinate within 21 days before slaughter. Do not mix with other products, except as specified on the label. Use entire contents when first opened. Inactivate unused contents before disposal. Contains streptomycin sulfate and penicillin as bacteriostatic agents and amphotericin B as a fungistatic agent.

Intraocular Vaccination

The vaccine used for intraocular vaccination is accompanied by diluent and is recommended for the vaccination of healthy chickens one day of age using the 1,000 dose or 2,000 dose vial.

1. Reconstitute each 1,000 doses of vaccine with 30 mL of diluent.

a. Remove aluminum seal and rubber stopper from vaccine vial and diluent vial. Avoid contamination of stoppers and contents.

b. Add diluent to half-fill the vaccine vial. Replace stopper in vial and shake it so that all contents are dissolved.

c. Pour the reconstituted vaccine into the diluent container. Replace stopper in diluent container and shake.

d. Remove stopper and fit drop-dispenser tip into diluent container.

2. Holding the diluent container with the dropper tip down, gently press the sides, dropping one drop of vaccine on the bird’s eye. Be sure the vaccine spreads over the eye before releasing the bird.

Coarse Spray Primary Vaccination Using Cabinet

Coarse spray primary vaccination using the cabinet application is recommended for healthy chickens at one day of age.

1. Do not open or mix vaccine until ready to vaccinate.

2. Reconstitute vaccine at a rate of 70 mL per 1,000 chickens using non-chlorinated water.

3. Each box of 100 chickens should receive approximately 7 mL of vaccine. The exact amount can be determined by spraying into a calibrated tube or container to arrive at the number of applications needed to deliver 7 mL of vaccine.

4. Whatever the volume of vaccine used, take care to administer a full dose to each chicken.

5. Allow chicks to dry; avoid chilling.

Drinking Water Vaccination Using Pouring Application

Drinking water vaccination is recommended for healthy chickens 14 days of age or older.

1. Remove all medications, sanitizers and disinfectants from the drinking water 72 hours (three days) prior to vaccination.

2. Provide sufficient waterers so that all the chickens can drink at one time. Shut off water supply and allow chickens to consume all the water in the lines.

3. Raise water lines above the chickens’ heads. Clean and rinse the waterers thoroughly.

4. Withhold all water from the chickens for a minimum of two hours in warm weather to four hours in cool weather prior to vaccination to stimulate thirst. Withdrawal time should be reduced if half-house brooding is in process.

5. Do not open or mix vaccine until ready to vaccinate.

6. Drinking water for vaccine delivery should contain 29 g (one ounce) of non-fat dry milk per 3.8 liters (US gallon) of non-chlorinated water, or should contain milk product based stabilizer prepared according to the manufacturer’s instructions.

7. Reconstitute the vaccine in 11 liters (3 US gallons) of milk-water during cool weather or 15 liters (4 US gallons) of milk-water during warm weather for each 1,000 doses.

8. Distribute vaccine solution among waterers. Avoid direct sunlight.

9. Lower waterers and allow the chickens to drink freely. Add the remaining vaccine solution to the water lines as the chickens drink.

10. Do not provide additional drinking water until all the vaccine is consumed.

Drinking Water Vaccination Using Proportioner Application

Drinking water vaccination is recommended for healthy chickens 14 days of age or older. Several types of medicator/proportioners are commercially available. Set proportioner to deliver 30 mL (one ounce) of vaccine concentrate per 3.8 liters (one US gallon) of water.

1. Remove all medications, sanitizers and disinfectants from the drinking water 72 hours (three days) prior to vaccination.

2. Clean all containers, hoses and waterers prior to vaccination.

3. Withhold all water from the chickens for a minimum of two hours in warm weather to four hours in cool weather prior to vaccination to stimulate thirst. Withdrawal time should be reduced if half-house brooding is in process.

4. Do not open or mix vaccine until ready to vaccinate.

5. Calculate to supply vaccine solution at a rate of 11 liters (3 US gallons) per 1,000 chickens in cool weather and 15 liters (4 US gallons) per 1,000 chickens in warm weather. The age of the chickens should be considered when calculating water supply. Always use non-chlorinated water when vaccinating chickens.

Example

1,000 chickens in cool weather x 11 liters (3 US gallons) = 11 liters (3 US gallons).

1,000 chickens in warm weather x 15 liters (4 US gallons) = 15 liters (4 US gallons).

6. Prepare vaccine stock solution as follows:

a. Determine the quantity of vaccine concentrate required by multiplying 30 mL (one ounce) x multiples of 3.8 liters (US gallons) of water needed for vaccine/drinking water.

Example

For 1,000 chickens: 3 volumes of 3.8 liters (3 US gallons) x 30 mL (1 ounce) = 90 mL (3 ounces).

b. Add 85 g (3 ounces) of non-fat dry milk per 480 mL (16 ounces) of cool water, or use a commercial milk product based stabilizer according to the manufacturer’s instructions. For 1,000 chickens add 16 g (0.5 ounces) non-fat dry milk to the 90 mL (3 ounces) of water.

c. Reconstitute the lyophilized vaccine with the milk solution. Rinse the vaccine vial to remove all the vaccine.

7. Insert proportioner hose into the vaccine stock solution and start water flow. Continue until all solution has been consumed before changing water supply to direct flow.

8. Do not medicate or use disinfectants for 24 hours after vaccination.

Coarse Aerosol Spray Application

Coarse aerosol spray application is recommended for vaccination of healthy chickens 14 days of age or older. Use a sprayer delivering a coarse aerosol spray pattern to dispense reconstituted vaccine quickly and evenly throughout a house of chickens. Do not use vaccinating equipment for any other purpose.

1. Prior to spraying, reduce air flow by raising curtains or stopping fans. Air movement should be limited for 20 minutes following vaccination.

2. Do not open or mix vaccine until ready to vaccinate.

3. Fill vaccine container with cool, distilled water.

4. Pour reconstituted vaccine into a clean container and add 150 mL (5 ounces) of cool water for each 1,000 chickens to be vaccinated.

5. Place the vaccine solution into spray canister and walk through the house spraying at the rate of 1,000 chickens per minute. Aim spray directly above the heads of the chickens.

6. Avoid direct contact with the vaccine solution. Wear goggles and mask while spraying.

Precautions

Do not vaccinate diseased chickens.

Vaccinate all chickens on the premises at one time.

Administer a minimum of one dose per chicken.

Avoid stress conditions during and following vaccination.

Do not place chickens in contaminated facilities.

Exposure to disease must be minimized as much as possible.

For veterinary use only.

In case of human exposure, contact a physician.

Notice

Boehringer Ingelheim’s vaccines have met the requirements of the USDA/CFIA in regard to safety, purity and potency, and efficacy. This vaccine has been tested by the master seed immunogenicity test for efficacy.

Newcastle-Bronchitis Vaccine, B1 Type, B1 Strain, Mass & Conn Types, Live Virus Caution

The capability of this vaccine to produce satisfactory results depends upon many factors, including - but not limited to - conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of individual chickens, and degree of field exposure. Therefore, directions for use should be followed carefully. The use of this vaccine is subject to applicable local laws and regulations.

THIS VACCINE IS NON-RETURNABLE

Manufactured by:

Boehringer Ingelheim Animal Health USA Inc., Gainesville, GA 30501 USA

VLN/PCN 124/1761.14

Distributed in Canada by:

Boehringer Ingelheim Animal Health Canada Inc., Burlington ON L7L 5H4

Product Codes NBD0313, NBD0373, NBD0320, NBD0350 and NBD0340

KD-1M/KE-2M/BK-5M/BL-15M/BN-25M

2050-5323-01

Presentation: Freeze-dried Vaccine: 50 x 2,000 dose, 25 x 5,000 dose, and 15 x 25,000 dose vials.

CPN: 1182105.5