Higher Risk for Death for Black Survivors of Second Primary Cancers
Medically reviewed by Drugs.com.
By Lori Solomon HealthDay Reporter
TUESDAY, Aug. 8, 2023 -- Among survivors of second primary cancers (SPCs), Black patients have the highest risk for death from both cancer and cardiovascular disease (CVD), according to a study published online Aug. 4 in JAMA Network Open.
Hyuna Sung, Ph.D., from the American Cancer Society in Atlanta, and colleagues examined racial and ethnic disparities in survival in 230,370 U.S. adults (aged 20 years and older) with SPCs (diagnosed 2000 through 2013 and followed for a median 54 months).
The researchers found that compared with the White population, the risk for cancer-related death overall was higher in the Black (hazard ratio [HR], 1.21) and Hispanic (HR, 1.10) populations but lower in the Asian or Pacific Islander population (HR, 0.93). The risk for cancer-related death was higher for 10 SPCs in the Black population, with the highest risk seen for uterine cancer (HR, 1.87). Elevated risk was seen for seven SPCs in the Hispanic population, particularly for melanoma (HR, 1.46). The overall risk for CVD-related death was higher in the Black population (HR, 1.41), including for 11 SPCs, while the risk for CVD-related death was lower in the Asian or Pacific Islander (HR, 0.75) and Hispanic (HR, 0.90) populations versus the White population. Similar associations for cancer-related death and for CVD-related death, albeit attenuated, were seen with further adjustments for county attributes and SPC characteristics and treatment.
"These findings suggest that research priorities to address survival disparities in the growing population of survivors of multiple primary cancers are warranted," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted August 2023
Read this next
Recommendations Issued for Palliative RT for Symptomatic Bone Mets
THURSDAY, May 30, 2024 -- In a clinical practice guideline issued by the American Society for Radiation Oncology and published online May 22 in Practical Radiation Oncology...
DNA Methylation-Based Epigenetic Age Mediates Link Between LE8 Score, CVD
WEDNESDAY, May 29, 2024 -- The associations between Life's Essential 8 (LE8) and cardiovascular health are mediated by DNA methylation-based epigenetic age, according to a study...
Living Outside of Comprehensive Cancer Center Catchment Area Tied to Later-Stage Diagnosis
TUESDAY, May 28, 2024 -- Disadvantaged populations and those living outside of a comprehensive cancer center's main catchment area have higher odds of receiving a diagnosis of...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.