• All News
• Consumer
• Pro
• New Drugs
• Pipeline
• Clinical Trials
• FDA Alerts

Adjustment for Risk Factors Cuts Black-White CVD Mortality Disparity

Medically reviewed by Drugs.com.

By Elana Gotkine HealthDay Reporter

TUESDAY, Aug. 15, 2023 -- The Black-White disparity in cardiovascular disease (CVD) mortality is attenuated after adjustment for behavioral and metabolic risk factors and is no longer significant after adjustment for social risk factors, according to a study published online Aug. 15 in the Annals of Internal Medicine.

Jiang He, M.D., Ph.D., from the Tulane University School of Public Health and Tropical Medicine in New Orleans, and colleagues examined the degree to which social, behavioral, and metabolic risk factors are associated with CVD mortality and their impact on racial differences in CVD mortality in a prospective cohort study that included a nationally representative sample of 50,808 persons aged 20 years and older.

The researchers confirmed 2,589 CVD deaths over an average of 9.4 years of follow-up. The age- and sex-standardized rates of CVD mortality were 484.7, 384.5, 292.4, and 255.1 deaths per 100,000 person-years in Black, White, Hispanic, and other race groups, respectively. After adjustment for all measured risk factors simultaneously, several social, behavioral, and metabolic risk factors were associated with significantly elevated risk for CVD death. The hazard ratios for CVD mortality for Black versus White participants were attenuated from 1.54 (95 percent confidence interval, 1.34 to 1.77) to 1.34 (1.16 to 1.55), 1.31 (1.15 to 1.50), and 1.04 (0.90 to 1.21), respectively, after adjustment for metabolic, behavioral, and social risk factors separately.

"Future research is warranted to understand the underlying mechanisms of social determinants of health on CVD mortality and develop novel interventions for reducing CVD mortality in populations, especially in Black persons," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Posted August 2023

More news resources

• FDA Medwatch Drug Alerts
• Daily MedNews
• News for Health Professionals
• New Drug Approvals
• New Drug Applications
• Drug Shortages
• Clinical Trial Results
• Generic Drug Approvals

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.