Sacrosidase Dosage

Medically reviewed by Drugs.com. Last updated on Sep 26, 2023.

Applies to the following strengths: 8500 units/mL; 8500 intl units/mL

Usual Adult Dose for Sucrase-Isomaltase Deficiency

Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or snack
Over 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snack

Comment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.

Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with congenital sucrase-isomaltase deficiency (CSID)

Usual Pediatric Dose for Sucrase-Isomaltase Deficiency

5 months and older:

Up to 15 kg: 1 mL (8500 international units) OR 1 full measuring scoop OR 28 drops orally per meal or snack
Over 15 kg: 2 mL (17,000 international units) OR 2 full measuring scoops OR 56 drops orally per meal or snack

Comment: Half the dose should be administered at beginning of meal or snack and the remainder during the meal or snack.

Use: Oral replacement therapy of genetically determined sucrase deficiency in patients with CSID

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS: Hypersensitivity to the active component, yeast, yeast products, glycerin (glycerol), papain, or to any of the ingredients

Safety and efficacy have not been established in patients younger than 5 months.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Rinse the measuring scoop with water after each use.
Do not add to warm or hot liquids; patients should not heat solutions containing this drug.
Do not reconstitute or consume with fruit juice.
This drug is fully soluble with infant formula, milk, and water.

Storage requirements:

Discard 4 weeks after opening due to the potential for bacterial growth.
Store in a refrigerator at 2C to 8C (36F to 46F).

General:

This drug is sensitive to heat.
This drug may contain small amounts of papain, which could result in allergic reactions.

Patient advice:

Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
Patients should be instructed to seek medical attention in the event of a hypersensitivity reaction.