Diphen Elixir Dosage

Generic name: DIPHENHYDRAMINE HYDROCHLORIDE 12.5mg in 5mL
Dosage form: oral solution
Drug classes: Anticholinergic antiemetics, Anticholinergic antiparkinson agents, Antihistamines, Miscellaneous anxiolytics, sedatives and hypnotics

Medically reviewed by Drugs.com. Last updated on Dec 13, 2023.

DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO THE NEEDS AND THE RESPONSE OF THE PATIENT.

A single oral dose of Diphen Elixir is quickly absorbed with maximum activity occurring in approximately one hour. The duration of activity following an average dose of Diphen Elixir is from four to six hours.

Always use a calibrated measuring device when administering Diphen Elixir to ensure the dose is measured and administered accurately.

Adults

Take 10 mL - 20 mL (25mg-50mg) three or four times daily. The nighttime sleep-aid dosage is 20 mL (50mg) at bedtime. Maximum daily dosage not to exceed 120 mL (300mg).

Pediatric Patients (over 20 lbs.)

Take 5 mL to 10 mL (12.5mg-25mg) three to four times daily. Maximum daily dosage not to exceed 120 mL (300mg). For physicians who wish to calculate the dose on the basis of body weight or surface area, the recommended dosage is 5 mg/kg/24 hours or 150 mg/m2/24 hours.

Data are not available on the use of Diphen Elixir as a nighttime sleep-aid in children under 12 years.

The basis for determining the most effective dosage regimen will be the response of the patient to medication and the condition under treatment.

In motion sickness, full dosage is recommended for prophylactic use, the first dose to be given 30 minutes before exposure to motion and similar doses before meals and upon retiring for the duration of exposure.