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Voydeya Disease Interactions

There are 2 disease interactions with Voydeya (danicopan).

Major

Danicopan (applies to Voydeya) infections

Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

Initiation of therapy with danicopan is contraindicated in patients with unresolved serious infection caused by encapsulated bacteria, including Neisseria meningitidis, Streptococcus pneumoniae, or Haemophilus influenzae type B. Complete or update vaccination against encapsulated bacteria at least 2 weeks prior to administration of the first dose of this drug; follow clinical vaccination guidelines for patients on complement inhibitors. Antibacterial drug prophylaxis is recommended in patients who require urgent therapy and who are not up to date on vaccinations.

References

  1. (2024) "Product Information. Voydeya (danicopan)." Alexion Pharmaceuticals Inc
Moderate

Danicopan (applies to Voydeya) liver dysfunction

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Avoid use of danicopan in patients with severe liver dysfunction (Child-Pugh C); studies have not been conducted in this population. No dose adjustment of danicopan is required in patients with mild to moderate liver dysfunction (Child-Pugh A or B).

References

  1. (2024) "Product Information. Voydeya (danicopan)." Alexion Pharmaceuticals Inc

Voydeya drug interactions

There are 193 drug interactions with Voydeya (danicopan).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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