Trintellix User Reviews & Ratings (Page 4)

• Whobe...
• Taken for 1 to 6 months
• May 25, 2019

For Major Depressive Disorder "This stuff Trintellix is pretty close to a miracle for me. I have had terrible reactions to SSRI’s to the point where I was told to not try anymore. I went through 2 long depressive periods, the last for several months with almost constant suicidal thoughts. My anxiety was at a level that I was frozen and isolated. I tried the Dr one last time. He prescribed this at 5mg Trintellix and .50 klonpine 2x daily. Within one week, I was completely myself again. Myself in a way I hadn’t been in years. I don’t feel drugged just normal with normal anxiety in appropriate situations but that’s lowered. I have not gained a pound. There was no nausea for me. The only issue was it does make me sleepy so I take a few hours before bed. So happy to have found this, I would urge anyone with issues with older SSRI’s to give it a shot"

• Crist...
• April 24, 2016

For Depression "I'm on Trintellix for a month and a half now. I've also been using Valdoxan for three months, but it didn't give any significant effect, so I've started taking Trintellix 10 mg, and after three weeks, I felt an effect. It seems like I'm getting better every day. My mood, energy level, and motivation have increased; my suicidal thoughts are gone, and I am finally able to cope with my everyday responsibilities."

• Mini
• Taken for 1 to 6 months
• November 23, 2021

For Depression "Took the full 8 weeks to adjust with a lot of stomach upset at first, but it gradually took away my anxiety which was making it hard to function. I was much better but still had some depressive thoughts/early waking (minus anxiety) - Doc explained 10mg treats anxiety, 15mg makes no difference and 20mg will treat the depression. So after a while I opted to level up and got some adjustment turbulence again for a couple of weeks - then I was all good. Much much better. Living life in a calmer and more constructive way. None of the sexual dysfunction side effects I got from escitalopram (lexapro - which was great for me othersiwe.) I swore I’d come back and review as I relied so heavily on reading these while I was waiting for relief. I won’t be putting myself back out in the cold with no meds ever again, it’s not pretty."

• Cat
• Taken for 1 to 6 months
• July 30, 2019

For Depression "First and foremost- one thing I have learned more than anything is that a medication is not a “cure all”. We need to do the work too with hobbies, therapy, self care, etc. But without this medication I may have not been able to do that. I had frighteningly severe social anxiety and couldn’t leave my house which led to depression and fed that cycle. I was honestly suicidal. Being fed up with living in misery and having tried literally all anti-depressants and anti-anxiety medications on the market before being 30 years old, this one finally let me breathe. I haven’t gained weight (what most people fear) I’ve actually LOST weight because I’m motivated to work out and eat well. I had a little constipation at first but drinking enough water helped that. My life is... a complete 180 of where I was two months ago. The only downside is that insurance is so awful to deal with in order to get on this!"

• Avera...
• April 4, 2019

For Depression "positives: Trintellix helped me manage my anxiety and depression for a time. I had a few good days where I felt almost normal. I was able to continue working full time and focus enough to “appear” normal. negatives: After 5 weeks on 10 mg I increased to 20 mg for a week and that was too much. I ended up in the ER and they recommended to stop the medication (after 6 weeks total). I’ve been off this med for 4 weeks and waiting for appointment in a few days to discuss another med. I’m sleeping a lot better now than before starting Trintellix, but I still have issues with depression and anxiety that affect my daily life. I used Zoloft 50 mg in the past for PPA but it wasn’t effective the 2nd time I tried it. Going to try another med, not ever going to give up. If you have read this far and are looking for encouragement, know that there is a med that will work for you and you will get better. There is hope, even if it doesn’t “feel” like it today."

• bobbya
• Taken for less than 1 month
• December 27, 2020

For Depression "Started on 5 MG daily for two weeks after taking wellbutrin 300 xl and duloxetine 20 daily which caused severe tinnitus and jaw pain and bruxism fracturing three teeth. Initially got some minor nausea but the jaw pain lessened and totally disappeared. I felt good with some minor anxiety. After 2 weeks increased to 10 mg daily. Again, then nausea returned but was gone on day four. I do have some jaw tension now but not too bad. I feel more alive. Doing tasks are easier. My spouse says I look more relaxed. On a scale of 1:10 I give myself a 6. Laughter comes naturally now. Sad movies give me a lump in the throat and tears. Thank God for Trintellix as it is returning my life to me."

• Scott...
• Taken for less than 1 month
• April 10, 2019

For Depression "Trintellix is great stuff, and glad I've finally found the drug that suits me. Been on Trintellix for nearly 2 weeks and my mood is so much better. Head is clear and I can get on with my day with no problems. I did have nausea for about 3 days but it's not that bad. No effect on sex drive or performance. It's worked for me. I hope it works for you"

• Juliez
• March 23, 2016

For Depression "Mid 30s with depression for over 4 years. Was on Lexapro 10mg, then 20mg for a little while, but it wasn't enough and the psych doc wouldn't listen to me or change my meds. So after 2 years of dealing with him, I switched to another psych doc who actually listened to me. First, she added Wellbutrin 150 then 300 XL. It wasn't such a great difference, so she switched me to Trintellix after insurance approval. She started me out at 5mg, then titrated up to 10mg, then 20mg. The first few days were the worst with side effects, but mine were nausea and diarrhea, that only got better in time. The feeling after being on this medication was great! I felt more like my old self again, happier, more motivated, less isolated, and got my sex drive back."

• Paul...
• Taken for 1 to 6 months
• February 11, 2019

For Depression "Reading so many other people having bad issues with this drug has me somewhat concerned. But at least for me so far, I am thrilled with Trintellix! It is not cheap but my insurance pays a good deal. And I have a good job. So I am completely willing to pay. I was taking Vibryd. But it stopped being effective. I have had no nausea or stomach issues. I have only been on it about a month. It was working much better than Vibryd within a week. I am much less irritable. No sexual side effects. I take this for both depression and OCD. It is not labeled for OCD. But antidepressants typically also work for OCD. And it does for me."

• Sherr...
• October 12, 2015

For Depression "I have literally been on every antidepressant made over the last six years trying to get my depression and anxiety under control. Every single time I had severe adverse side effects, except with Lexapro which worked amazing for about six months. I had given up on medication, but my symptoms persisted and I hit a low and knew I had to do something. I am hypersensitive to medication, and because of my past side effect issues, my new PCP gave me samples of Trintellix, starting at 5 milligrams. I immediately felt better and had zero side effects, so when I had a follow-up visit a week later, she bumped it up to 10 milligrams. Two weeks on the new dose and I feel amazing. I feel like me again. Best med I've used!"

• Steven...
• Taken for 1 to 6 months
• November 11, 2018

For Depression "I am a 51 year old male and have tried everything too. I started trintellix a month ago with 5mgs. I did experience some stomach issues for one day. After a week, I went up to 10mgs. After another week, with my doctor’s ok, I went up to 15mgs. No side effects. I am now on 20mgs and am feeling better than I have felt in a long time. Sleeping well and zero depression. All medication is different for different people but I am truly happy on Trintellix and keep working with your doctor to find a way out of depression. There is something that will work for you."

• ricks...
• Taken for 5 to 10 years
• January 14, 2024

For Major Depressive Disorder "I had major depressive disorder for decades and had been on every antidepressant med., so when I saw a psychiatrist (2014 or 2015) at the insistence of my psychologist, the psychiatrist confirmed that I had been on every antidepressant med. with, at most, brief benefit. She suggested trying a new med., which was originally called Brintellix. My depressive symptoms had included long periods - weeks, months - of extreme depression in reaction to even minor triggering events. I was in one of the long periods of extreme depression when I began taking this medication. The morning after my first dose, I was relieved of the intensity and even of a mildly depressed affect. Since then, I have had brief periods of very disturbing depression, but they have been only periods of hours. I have not had any periods of depressive affect or behavior lasting more than a few hours. I have had mild symptoms from time to time, but none where I could not function. I can still feel hopeless or sometimes."

• John
• Taken for 1 to 6 months
• May 14, 2024

For Major Depressive Disorder "74-year-old white male (Retired MD) with multiple years of major depression. No meds until retired at age 70, then prescribed multiple medication treatments, settling on Trintellix 20 mg qam for 4 months. It took at least 3 months before noticing any change. Abilify 5 mg qam was added at 3 months, after which improvement in depression, attitude, and sleep patterns were noticed. During the first 2 months, experienced severe and frequent suicidal thoughts (wrote the letter twice), with no other side effects. If not for my 401k, I could not afford the $300 per month for Trintellix and $200 per month for Abilify. I have been contemplating stopping both medications and trying to manage without them. Unsure whether the depression of life is worse than the depression of depleting my hard-earned 401k. If I were single (widowed), I would definitely consider stopping the medications due to concerns about financial stability. Being old, depressed, and grumpy seems better than being old, depressed, and impoverished."

• Bern
• April 6, 2019

For Depression "I am not one to tattle on drugs or make blanket statements but I had a horrible experience on Trintellix. Sobbing uncontrollably and wanted to kill myself. Went into the darkest of places on this drug. Immediate relief when I came off if it. I am sure it works for some people. Unfortunately, I had a terrifying experience with it."

• midLi...
• Taken for 1 to 6 months
• April 16, 2015

For Depression "This medicine saved me! I have always been a very happy and successful person. Depression and anxiety were not a part of my life until I hit 43. So I went to doctors and they had me try a few other meds, Zoloft, etc. I didn't see any positive effect from them, just the problems...lack of sleep, night sweats, sexual problems, etc. Things were getting worse. Then, my doctor put me on this medication and everything changed. First, I started getting headaches for a few days. That went away by the end of the first week. I started on 5mg and then went to 10mg after a week. By the end of week two, my panic attacks were GONE! I still 'think' about my problems, but don't obsess about them. This is a GOOD medicine!"

• LCPC
• August 15, 2019

For Depression "As a therapist I have recommended Trintellix for my clients and have listened to doctor led seminars on this medication. As I have read some comments I was surprised how many patients expected Trintellix to help with their anxiety or docs who prescribed it maybe for that as it does not treat anxiety so it would have no direct influence for anxiety only depression."

• Feeling...
• April 26, 2017

For Depression "I have been on many antidepressants and they all make me want to snack and overeat. I gained a lot of weight on all of the other antidepressants. I was so tired of gaining weight. About a year ago, I started taking Trintellix and I am no longer craving snacks all day. My depression was marked by feelings of irritability and lots of crying. I feel 100% better. I think that this medication has worked better than any others I've tried. So relieved."

• RJano
• Taken for 1 to 6 months
• May 11, 2019

For Depression "I have suffered from depression off and on since my teenage years. I've tried literally dozens of psych meds over the last 30 years and had no relief. I started on Trintellix with Wellbutrin XL and I feel great. I started to see results within a week. I have now been on it for three months, and still very happy with it. My mood is great, I have energy and motivation. For me, it's been a miracle drug."

• Hek
• Taken for 1 to 6 months
• January 22, 2017

For Depression "Taking it since one month because of a reactive depression for over a year. I have never taken anti-depressants before and kept refusing although my psychologist urged me to for several months. When the depression kept getting darker: no energy, sad, bad insomnia and constant thoughts of suicide (which my psychologist didn't know) I decided to take the advice to start on Trintellix (was either that or kill myself). The first 4 days I was so tired I spent most of the time in bed. Then I just started to feel better and better. High energy level, creative, not sad, no mood swings, slept great at night and best of all the suicidal thoughts just disappeared. I started and stayed on 5 mg. No side effects at all, working night shift no problem!"

• CatCh...
• May 16, 2015

For Depression "I've been severely depressed for 10 years inc 2 hospital stays. My psychiatrist is excellent and suggested brintillex After I've been on cymbalta for 2 years. Already so much less sleepy, more prone to complete tasks, not moping around all day and I have hope. Only one side effect is skin itching I can't seem to stop it! But other than that very happy. If you've given up on life, the future, any chance of recovery give it a try."

• Nikki
• Taken for less than 1 month
• February 13, 2020

For Depression "Was switched to Trintellix from Citalopram as it interfered with an antibiotic I needed. I have been on it for 3 weeks now. Absolutely horrible! I have never felt this crazy. I feel like I am loosing my mind. Constant panic attacks, sensitivity to even the slightest sounds, lightheaded/dizziness, nausea, suicidal ideations, difficulty breathing. I am suffering from severe mood swings. I stopped taking it tonight. Just can’t do it anymore. I rather have nothing than this."

• Audix...
• June 10, 2015

For Depression "I've been battling MDD for about ten years now, and I've been on and off many different medications. My biggest complaint with most of them was the fatigue. I'm only 24, but while I was on this medication, it was hard for me to keep up with my friends who were similar ages. I was always tired, always taking naps, and still going to bed early. With Trintellix, the fatigue is GONE! It's easier for me to wake up, I can do more during the day without wanting to take a nap, and having more energy has given me the opportunity to start exercising again. I do have a bit of stomach upset while taking it, but it is mild and, frankly, a small price to pay when considering all the good Trintellix does for me."

• Kay
• Taken for 6 months to 1 year
• July 1, 2020

For Depression "Started Trintellix in a VERY LOW DOSE.. seemed to help. After 3 months, didn’t seem to help at all. Increased my dose, then the vomiting, weight gain went crazy!! Had to leave work several times because of vomiting!! I am a nurse in a VERY busy emergency department!! Grateful they didn’t fire me! Then the weight gain - up 20 LBS!! They claimed “ no significant effect on weight”.. LYING!!! Never again.. weaned off.. I’ll deal with being sad!"

• Middle...
• March 15, 2017

For Depression "One month on 5mg of Trintellix. I was on Zoloft for 3 years and was a zombie. It is like a veil has been lifted. I have energy like I did when I was in my 20s. I also can see I am clearly surrounded by critical, condescending people. I never was able to give much thought to their behavior while on Zoloft. I am experiencing a euphoric feeling that was absent prior to Trintellix."

• eliza...
• August 9, 2016

For Major Depressive Disorder "This medication is a game changer. I've been on 20 mg once per day (at night works best for me) for about 5 months. It is by far the best medication I have tried. Initially started on 10 mg, and raised my dose 2 months in. Pros: Overall heightened mood, more energy, ability to feel array of emotions, no sexual dysfunction (many antidepressants are famous for causing this), increases ability to enjoy activities I used to love. Neutral: does not treat my anxiety very well alone. Cons: nausea when starting the medication and increasing dose, more expensive than traditional antidepressants. Overall, I love this medication. I will definitely continue on it. I have seen a big improvement since trying Trintellix."