Duloxetine User Reviews & Ratings (Page 5)

• WSR
• Taken for 1 to 6 months
• July 28, 2020

Cymbalta (duloxetine) for Osteoarthritis "CYMBALTA changed my life. I started using Cymbalta for severe chronic lower back pain. My pain was so bad I considered suicide on many occasions. After failed back surgery, over the counter medications, epidurals, spinal ablation and everything else imaginable, my pain doctor prescribed Cymbalta. The side effects from Cymbalta were horrible, but within 2 weeks my back pain completely disappeared. I still deal with the side effects and Cymbalta is a highly addictive drug that is near impossible to withdraw from. I have come to terms with the alternatives and have decided Cymbalta is worth all of the negatives. It has saved my life."

• g0ldon
• November 16, 2018

Cymbalta (duloxetine) for Anxiety "I had a large but benign brain tumor removed a year and a half ago. After my recovery, I had depression and anxiety which I had never really had before. After dealing with it over a year, I started generic Cymbalta 3 months ago. First 2 months 30 mg a day. Some initial insomnia, 1 day of upset stomach, loss of appetite (lost 8 lbs) for about 3 weeks. Helped immediately with depression, anxiety issues took about 5 weeks. After 2 months, Dr put me on 60 mg a day which I've taken for 4 weeks now. Anxiety is so much better, feel it coming on now and then but it doesn't last. I've put the weight back on but nothing extra. Sleeping 6-7 hours a night, about average for me. This drug overall has really helped me, I take nothing else with it. I'm sorry to hear it effects some people so negatively, but please try to stay on this until your body can get used to the side effects. This drug has greatly improved my life."

• Socal...
• Taken for 1 to 6 months
• October 26, 2017

Cymbalta (duloxetine) for Chronic Pain "3 Months and so far this drug has helped me more than PT, steroid shots, yoga, massage, traction, ibuprofen and patience. The side effects were challenging to begin with, but once the first few weeks had passed by, I was feeling pretty normal and back to my old self again. I can't describe how grateful I am for this medication and it's helped me to no end. Don't believe all the negative reviews, but take note of the positive reviews too."

• Krstn...
• Taken for less than 1 month
• February 28, 2021

Cymbalta (duloxetine) for Depression "I was prescribed 30mg a day by my doc. I took my first dose after dinner as suggested. Around 4am I woke up and the room was spinning. I had pain in my stomach as if I had food poisoning. I wasn't able to fall asleep and I didn't get up because I knew I would vomit. I took another dose next day and I experienced shivering, chills, sweaty palms, anxiety, dilated pupils. I thought maybe it would improve or subside, but the third day I woke up, looked on the mirror and a gaunt, pale face with large pupils was staring back at me. I jumped in the shower and was shivering so badly I thought I would go into cardiac arrest right then and there. I should've went to the ER. I was so scared. I stopped the med immediately. My doc switched me to lexapro and I filled the script but I'm too shaken up from my exp with Cymbalta I'm holding off until I feel myself again. I'm in recovery and I haven't felt like that on any drug in the past. Quite unnerving. Never again. And don't recommend."

• CJano
• June 15, 2019

Cymbalta (duloxetine) for Depression "I am prescribed this medication for over-focused ADHD and depression. Before trying this medication I was on Adderall once, and Modafinil once, all for a short time. The Cymbalta medication has really helped me. The pain of depression is gone, my thoughts are in a better scope, and I don't feel as deeply and get into moods. While not feeling as deeply might sound bad to some people, it is a real issue for me. With my depression at bay I'm much more able to focus on what I need to do and do it with a good attitude. I notice I don't obsess over things as much and am able to be present in the moment, and easily change my train of thought to the next thing. I'm very happy I trusted my doctor on this, because at first I really didn't like the idea. I know this is temporary, but I trust in the medication to put me in a safe place. Understand that the bad reviews are obvious in that some people were simply misdiagnosed. I have no negative side effects at all."

• Fated...
• Taken for 2 to 5 years
• April 21, 2020

Cymbalta (duloxetine) for Major Depressive Disorder "I’ve been taking the generic Cymbalta for just over four years now to help manage my Major Depressive Disorder* My current maintenance dose is three 30mg capsules taken by mouth once daily, which totals to a 90mg dose/day. Overall, I’d say my experience with Cymbalta has been a positive one. I don’t particularly suffer from any of the listed side effects. Compared to other anti depressant-type medications, in my opinion, I would say Cymbalta in particular “kicked in,” the fastest, to where I started feeling better than the previous anti depressants I’ve been prescribed in the past. Cymbalta isn’t the common SSRI we’re all familiar with, this medication is an SNRI, which means it not only works to boost your Serotonin, but also Norepinephrine (also known as Noradrenalin and/or Noradrenaline). I personally find for my body/my brain, I do better with SNRIs than with SSRIs, but that’s just me personally."

• Heidigr
• July 23, 2018

Cymbalta (duloxetine) for Fibromyalgia "I have had significant joint pain ongoing since 2012. I was diagnosed with rheumatoid arthritis and spent the next three years going through a host of every med available. None of them worked and many made it worse. I went to the Mayo Clinic in 2016. The top RA doc there, after running many tests, said he didn’t think I had RA, but Sjogren's disease. He suggested I try Cymbalta for pain, but was so tired of meds that I honestly just toughed it out until a few months ago. I have been in excruciating pain - mainly my feet and hand joints for six years. I grudgingly found another RA doc who would treat me (Mayo wouldn’t) and the first thing he said is that he felt my autoimmune condition was likely fibromyalgia and suggested I try the Cymbalta. Amazingly, it has been a complete game changer. Within the first month, I could tell it was working. I am now in almost zero pain and have had no side effects that are worth mentioning. I have nothing but positive things to say about this medication."

• Chiara
• Taken for 1 to 6 months
• May 23, 2024

For Persistent Depressive Disorder "I have tried every antidepressant on the market, you name it: Prozac, Effexor, Zoloft, Wellbutrin, Pregabalin. I suffer from depression, general anxiety, sadness, poor self-esteem since I can remember. Plus a lot of personal traumatic experiences made me really hopeless and terribly harsh on myself. Every time my doctor switched medication, I came here to read only the positive reviews and every time I read 'it was a life changer' I was filled with hope. Sadly, none of them was a life changer for me and I thought that my brain and body were just not responding to medications. Until she prescribed me Duloxetine, which I took with very poor trust, feeling at the lowest in my life. Well, believe me or not, in 48 hours I felt a real, tangible change in my mood. I started looking at life differently, feeling generally better even if my current situation was basically the same. Most of all, I stopped beating myself up for good. Today I can finally say 'it was a life changer'. Give it a try!"

• DSummer
• Taken for 10 years or more
• June 30, 2019

Cymbalta (duloxetine) for Depression "I have been taking Cymbalta for approximately 15 yrs. for depression & anxiety. I had tried every other drug on the market. It has been a life saver for me! The first few days I felt nauseous but that is a side effect that goes away. My dr told me it was one of the few that continues to work after taking it for a long time. I mistakenly have quit taking it a few times to see if I felt better. I had no adverse effects coming off of it except that my anxiety & depression worsened. This year was the first time I’ve had my dosage increased since starting the med. As long as it continues to work, I’ll never quit taking it."

• Austr...
• Taken for 1 to 6 months
• March 17, 2021

Cymbalta (duloxetine) for Anxiety "I feel so lucky, this has gone beyond my expectations. I don’t ever want to be off it. Only side effect has been constipation but I feel so good I don’t care. Even if I forget to take the tablet I have NO SIDE EFFECTS! I was really hesitant to start this as the reviews didn’t seem so good but it truly is an individual experience."

• wfelici
• Taken for 2 to 5 years
• September 29, 2014

Cymbalta (duloxetine) for Depression "EXCELLENT results. Effexor became non-effective after many years of use and another life-impacting event. Was recently severely depressed and suicidal for about 2 years. Found Cymbalta 2 years ago, and it CHANGED MY LIFE FOR THE BETTER. I think this medication is FANTASTIC. I have been diagnosed with major depressive disorder and general anxiety disorder (dual diagnosed). This condition has been with me for many years (runs in the family, i.e., mother was severely depressed). Cymbalta 120mg per day snapped me out of it. Under doctor's orders, I discontinued the current SSRI at the time and started right up with Cymbalta 120mg/day. Within 7-10 days, I was out of my depressed state. It has to be the norepinephrine aspect that made the difference."

• Jan
• Taken for 10 years or more
• September 17, 2019

Cymbalta (duloxetine) for Depression "I have been on Cymbalta for ten years. It immediately helped my fibromyalgia pain and worked awesome for my depression. I was on 60mg for about 5 years and now on 90mg 5 years. I tried to come off it so for one month I took 60mg last February. The symptoms were unbearable. I felt bee stings everywhere and I literally mean everywhere. My legs were in soo much pain my whole body felt like it was shaking inside. I had flushing a fever non stop itching. The list goes on. It definitely served a wonderful purpose when I started, I just kinda feel cheated they didn’t tell me I have to stay on for the rest of my life. "

• Jaye
• September 6, 2018

Cymbalta (duloxetine) for Anxiety "I had pain throughout my entire body I felt like I was dying. My moods were at an all time low for months. No ambition just wanted to sleep and give up on life at age 45. I had been on other medicines for several years they worked ok but I still had issues. I just tried to cope with them until it became too much. I am on day 2 of Cymbalta 60mg and I can already feels the difference. I wake up feeling alive and I’m not hurting all over my body. My mentality is about 80% better already. Thank goodness this worked!! I hope it helps others as much as it has helped me!"

• MomoR...
• May 15, 2017

Cymbalta (duloxetine) for Anxiety "I feel like some of you people commenting on how inept the doctors are at prescribing medication for you fail to realize how medications affect people differently. You had a bad experience? That is in no way, shape or form the doctor's fault. At all. Your body chemistry is just different than they expected. These psychiatric issues are not an exact science. Medicine is not an exact science. That aside, I've only been on Cymbalta for about a month, but I have already noticed a vast improvement. I feel less anxious overall and haven't experienced a panic attack since I started on it. Again, this isn't an exact science, and sometimes it takes experimentation to get the right combination. Hopefully, I've found a proper solution to my issues."

• Judy
• Taken for 10 years or more
• June 20, 2019

Cymbalta (duloxetine) for Fibromyalgia "I suffered from the pain of fibromyalgia for 20 years and I got my life back after I started to use Cymbalta. I have no more pain, other than that of many 71 year olds. I consider myself one of the very fortunate people that it works so well for me. I can take fitness classes now and feel the improvement from them tremendously. I also think that what likely helped me work etc. when I had the symptoms was the fact that I did mild exercise six mornings a week for 20 min. on the recommendation of an amazing doctor who recognized what I had before most people had even heard of it and told me exercise was supposed to help. I walked up and down my stairs then used a cross trainer (slowly) - when my husband decided I was wearing out our carpet!"

• Cymba...
• April 23, 2017

Cymbalta (duloxetine) for Depression "Cymbalta has been an incredible drug for me. Since taking Cymbalta, I have been able to enjoy life more, sleep less, and feel more refreshed - reduction in pain, and improved memory and concentration. Recently, I have been studying for an exam. This is a hard exam that I previously failed before while not taking Cymbalta. I started taking Cymbalta approximately in January. The months leading up to the exam, I was more focused and able to concentrate better than I can last remember. I know that Cymbalta doesn't treat concentration or memory problems, but I think that sometimes if you are depressed, it can have a severe effect on concentration. Thank you, Cymbalta, for helping me in my life."

• Danid...
• June 17, 2015

Cymbalta (duloxetine) for Generalized Anxiety Disorder "I have been on Cymbalta for a week now, 30mg twice a day. I have no side effects at all! From the first dose, I noticed a huge difference; it calmed me right down! Before this med, I was mad at everything, almost in a constant panic mode, not sleeping, and in a lot of pain. I have low back nerve pinching, bulging, degenerative discs, and fibromyalgia. I can't say enough good about this medicine; it has really changed my quality of life, my outlook. I feel like I did 20 years ago, before my anxiety took over my mind. My blood pressure is also back to normal. Being stressed at every little thing made mine go up. I love this medication; I wish I had gotten it a lot sooner, better late than never!!"

• boome...
• Taken for 1 to 6 months
• August 26, 2019

Cymbalta (duloxetine) for Chronic Pain "I have been on Cymbalta for two months, 60mg in the morning. The first week I was on 30mg to give my body a chance to get used to the drug. I have had no side effects, except maybe a little constipation the first week or two. I am taking it for chronic pain from osteoarthritis in neck and lower back. I do suffer from anxiety and mild depression. My fingers were killing me two months ago. Now when I make a fist the fingers are a little stiff but no pain. My neck pain has been more manageable. I am still having issues with lower back joint dysfunction. I generally feel more optimistic, don't get aggravated at bad drivers, take things a little more easy and have more energy to get things done. My motivation is coming back. I am only rating an 8 at this point since it has only been two months."

• theuser
• Taken for less than 1 month
• December 18, 2018

Cymbalta (duloxetine) for Generalized Anxiety Disorder "I have tried a loooong list of antidepressants, including older ones, newer ones and most of the meds in between. Cymbalta is the only one that has helped me. I have only taken it for about a week but I already feel the effects for my GAD and Panic Disorder. I am so thankful for this drug. Bless you all, don't be afraid to try meds and keep on fighting if you haven't found one that has worked for you yet. Hugs, The User"

• Trekk
• Taken for 6 months to 1 year
• September 30, 2019

Cymbalta (duloxetine) for Depression "The most important thing I want to share here is that it is the most addictive substance I have ever taken (And I have tried at least 100 different drugs.) It's not addictive because of the benefits it gives. It's addictive as anything because when you forget to take a pill - all the hell break loose. I highly do not recommend this to anyone. If you consider taking it - DO NOT! UNDER ANY CIRCUMSTANCES. Better be sick from your illness then get another illness because of this medicine. Do some online research about CYMBALTA HURTS WORSE"

• Rsano
• Taken for less than 1 month
• July 20, 2019

Cymbalta (duloxetine) for Back Pain "I started 30mg cymbalta 3 weeks ago for my neck and lower back pain. I feel so much better now. I went through weird side effects and lost appetite. I was afraid to take this medication after reading the reviews but everyone is different. I’ve been able to work and workout without pain. Cymbalta worked pretty good for me."

• Ginip
• June 13, 2015

Cymbalta (duloxetine) for Depression "My experience on Cymbalta has been rather a positive one. As mentioned by others, in the first 2 weeks, it does have side effects. I felt tired and was a little nauseous. I was put on Cymbalta as the entire country that I live in ran out of my previous medicine. I have suffered from anxiety, OCD, and depression on and off for a few years. Since Cymbalta has 'kicked in,' I have hardly any anxiety and no depression. I think clearly and rationally and not as emotionally as I always used to. I still do not have an appetite, and I have been on this for over a month now. When I sleep, I sleep soundly and am able to fall into a deep sleep as well. I highly recommend Cymbalta and am very happy with the positive effects it has had on me."

• Bluef...
• Taken for 2 to 5 years
• March 8, 2019

For Pain "I've been on Duloxetine about 5 years (@ 60 mg/day), and want to encourage people considering trying it not to be scared off by negative reviews. I do believe the negative reviews are (generally) legitimate, and that a lot of people have had negative experiences. Their voices are also critical (as are all patient's) in helping to create awareness. But I believe the experience most people have with duloxetine is not dramatic. It either helps (sometimes a lot; other times just enough to keep taking), or doesn't. It helped significantly in my case, making my pain bearable, allowing mostly-normal day-to-day activities. I did have initial drowsiness (which went away in 10 days - 2 weeks), and nausea (still have occasionally), dizziness & balance issues (still remain, but not major). Don't be afraid to try Duloxetine, it presents a reasonably good chance to provide you with meaningful relief. Best of luck:-)"

• onewo...
• April 2, 2009

Cymbalta (duloxetine) for Depression "I feel the need to warn people about the withdrawal symptoms of getting off of this drug. I am home right now because I feel nauseated, my coordination is way off. I have severe head shock, and can't sleep. Look for these types of stories before taking these types of medicines."

• Xyz
• May 6, 2021

Cymbalta (duloxetine) for Anxiety "I’ve been on Cymbalta for almost two weeks. The first few days were a little tough. My mind was racing a bit and I had tension in my throat and jaw. I was a bit more anxious those first couple of days but it got a little better and I feel SO much better. I’ve tired Zoloft which made my anxiety worse, then Citalipram which didn’t really do much of anything except make me restless and jittery but Cymbalta is finally the right one. I feel like a normal person for the first time in a long time. My piece of advice, I see a lot of people on here saying that they’ve felt miserable for 3-4 weeks, even a month +. That’s too long in my opinion, I was told if you’re still miserable 2 weeks in, tell your doctor and switch it up your meds."