SVS 510 (Canada)

Company: Merial

Bursal Disease Vaccine

Standard & Variant

Live Virus

SVS 510 Indications

This vaccine contains live bursal disease viruses. This vaccine is recommended for vaccination of healthy chickens at one day of age by the subcutaneous route or at seven days of age or older using the drinking water or coarse aerosol spray. It is essential that the chickens be maintained under good environmental conditions and that exposure to disease viruses be reduced as much as possible.

USE ONLY IN LOCALITIES WHERE PERMITTED. USE ONLY IN FLOCKS WITH A HISTORY OF INFECTIOUS BURSAL DISEASE.

READ FULL DIRECTIONS CAREFULLY

Store vaccine at 2-7°C (35-45°F). Do not freeze. Do not vaccinate within 21 days before slaughter. Use entire vial contents when first opened. Burn this container and all unused contents. Contains streptomycin sulfate and penicillin as bacteriostatic agents and amphotericin B as a fungistatic agent.

Preparation Of Vaccine For Subcutaneous Injection

IMPORTANT: Sterilize vaccinating equipment by autoclaving 15 minutes at 121°C (250°F) or by boiling in water for 20 minutes. Never allow any chemical disinfectant to come in contact with vaccinating equipment.

1. For each 1,000 doses of vaccine, use 200 mL of sterile diluent.

2. Do not open and reconstitute the vaccine until ready to start vaccinating.

3. Tear off the aluminum seal from a bottle of diluent and remove the stopper.

4. Using a sterile syringe, remove 2 mL of diluent and add to the lyophilized vaccine.

5. Allow the vaccine to dissolve, and transfer the dissolved vaccine back into the bottle of diluent.

6. Rinse the vaccine vial to be sure of removing all the vaccine.

7. Replace the stopper and thoroughly mix the vaccine and diluent by swirling and inverting.

8. Use the vaccine-diluent mixture immediately as described below.

SUBCUTANEOUS INJECTION METHOD

1. Use a sterile automatic syringe with a 20-22 gauge, 3/8-1/2 inch needle that is set to accurately deliver 0.2 mL. Check the accuracy of delivery several times during the vaccination procedure.

2. Dilute the vaccine only as directed, observing all precautions and warnings for handling.

3. Keep the bottle of diluted vaccine in an ice bath and agitate continuously.

4. Hold the chicken by the back of the neck, just below the head. The loose skin in this area is raised by gently pinching with the thumb and forefinger. Insert the needle beneath the skin in a direction away from the head. Inject 0.2 mL per chicken. Avoid hitting the muscles and bones in the neck.

5. Use entire contents of bottle within one hour after mixing.

Directions For Addition Of Blue Dye To Sterile Diluent

Blue dye may be aseptically added to sterile diluent using the following procedures:

1. Dye mixing chart:

2. Swab top of rubber stoppers on dye vial and diluent container with alcohol; let dry.

3. Using a sterile syringe and needle, withdraw the contents of the vial.

4. Inject dye into diluent container and mix well.

5. Only Merial’s vaccines may be used with this diluent. Add vaccine according to the manufacturer’s recommendations.

6. Properly dispose of the dye container and any unused contents at the end of the day.

Drinking Water Vaccination Using Pouring Application

Drinking water vaccination is recommended for healthy chickens seven days of age or older.

1. Remove all medications, sanitizers and disinfectants from the drinking water 72 hours (three days) prior to vaccination.

2. Provide sufficient waterers so that all the chickens can drink at one time. Shut off water supply and allow chickens to consume all the water in the lines.

3. Raise water lines above the chickens’ heads. Clean and rinse the waterers thoroughly.

4. Withhold all water from the chickens for a minimum of two hours in warm weather to four hours in cool weather prior to vaccination to stimulate thirst. Withdrawal time should be reduced if half-house brooding is in process.

5. Do not open or mix vaccine until ready to vaccinate.

6. Drinking water for vaccine delivery should contain 29 g (one ounce) of non-fat dry milk per 3.8 liters (US gallon) of non-chlorinated water, or should contain milk product based stabilizer prepared according to the manufacturer’s instructions.

7. Reconstitute the vaccine in 11 liters (3 US gallons) of milk-water during cool weather or 15 liters (4 US gallons) of milk-water during warm weather for each 1,000 doses.

8. Distribute vaccine solution among waterers. Avoid direct sunlight.

9. Lower waterers and allow the chickens to drink freely. Add the remaining vaccine solution to the water lines as the chickens drink.

10. Do not provide additional drinking water until all the vaccine is consumed.

Drinking Water Vaccination Using Proportioner Application

Drinking water vaccination is recommended for healthy chickens seven days of age or older. Several types of medicator/proportioners are commercially available. Set proportioner to deliver 30 mL (one ounce) of vaccine concentrate per 3.8 liters (US gallon) of water.

1. Remove all medications, sanitizers and disinfectants from the drinking water 72 hours (three days) prior to vaccination.

2. Clean all containers, hoses and waterers prior to vaccination.

3. Withhold all water from the chickens for a minimum of two hours in warm weather to four hours in cool weather prior to vaccination to stimulate thirst. Withdrawal time should be reduced if half-house brooding is in process.

4. Do not open or mix vaccine until ready to vaccinate.

5. Calculate to supply vaccine solution at a rate of 11 liters (3 US gallons) per 1,000 chickens in cool weather and 15 liters (4 US gallons) per 1,000 chickens in warm weather. The age of the chickens should be considered when calculating water supply. Always use non-chlorinated water when vaccinating chickens.

EXAMPLE

5,000 chickens in cool weather x 11 liters (3 US gallons) = 55 liters (15 US gallons).

5,000 chickens in warm weather x 15 liters (4 US gallons) = 75 liters (20 US gallons).

6. Prepare vaccine stock solution as follows:

a. Determine the quantity of vaccine concentrate required by multiplying 30 mL (one ounce) x multiples of 3.8 liters (US gallons) of water needed for vaccine/drinking water.

Example

For 5,000 chickens: 15 volumes of 3.8 liters (1 US gallon) x 30 mL (1 ounce) = 450 mL (15 ounces).

b. Add 85 g (3 ounces) of non-fat dry milk per 480 mL (16 ounces) of cool water, or use a commercial milk product based stabilizer according to the manufacturer’s instructions. For 5,000 chickens add 75 g (2.5 ounces) non-fat dry milk to the 450 mL (15 ounces) of water.

c. Reconstitute the lyophilized vaccine with the milk solution. Rinse the vaccine vial to remove all the vaccine.

7. Insert proportioner hose into the vaccine stock solution and start water flow. Continue until all solution has been consumed before changing water supply to direct flow.

8. Do not medicate or use disinfectants for 24 hours after vaccination.

Coarse Aerosol Spray Application

Coarse aerosol spray application is recommended for vaccination of healthy chickens seven days of age or older. Use a sprayer delivering a coarse aerosol spray pattern to dispense reconstituted vaccine quickly and evenly throughout a house of chickens. Do not use vaccinating equipment for any other purpose.

1. Prior to spraying, reduce air flow by raising curtains or stopping fans. Air movement should be limited for 20 minutes following vaccination.

2. Do not open or mix vaccine until ready to vaccinate.

3. Fill vaccine container with cool, distilled water.

4. Pour reconstituted vaccine into a clean container and add 150 mL (5 ounces) of cool water for each 1,000 chickens to be vaccinated.

5. Place the vaccine solution into spray canister and walk through the house spraying at the rate of 1,000 chickens per minute. Aim spray directly above the heads of the chickens.

6. Avoid direct contact with the vaccine solution. Wear goggles and mask while spraying.

Precautions

Do not vaccinate diseased chickens.

Vaccinate all chickens on the premises at one time.

Administer a minimum of one dose per chicken.

Avoid stress conditions during and following vaccination.

Do not place chickens in contaminated facilities.

Exposure to disease must be minimized as much as possible.

For veterinary use only.

Notice

Merial’s vaccines have met the requirements of the USDA/CFIA in regard to safety, purity, and potency. This vaccine has been tested by the master seed immunogenicity test for efficacy.

SVS 510 Caution

The capability of this vaccine to produce satisfactory results depends upon many factors, including - but not limited to - conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of individual chickens, and degree of field exposure. Therefore, directions for use should be followed carefully. The use of this vaccine is subject to applicable state and federal laws and regulations.

THIS VACCINE IS NON-RETURNABLE

MERIAL, INC., Athens, GA 30601 USA

U.S. Vet Lic. No. 298

Product Codes GVD-1020 and GVD-1040

W-5M / Y-25M

2050-1235-01

Presentation: 10 x 5,000 doses.

CPN: 1182109.2