Sedentary Time in Childhood Tied to High Cholesterol in Adulthood
By Lori Solomon HealthDay Reporter
FRIDAY, Dec. 22, 2023 -- Sedentary time during childhood is tied to worse lipid profiles in young adulthood, according to a study published online Dec. 14 in the Journal of Clinical Endocrinology & Metabolism.
Andrew O. Agbaje, M.D., M.P.H., from the University of Eastern Finland in Kuopio, examined the associations of sedentary time, light physical activity (LPA), and moderate-to-vigorous PA (MVPA) from childhood through young adulthood with lipid levels. The analysis included 792 children (age 11 years) participating in the Avon Longitudinal Study of Parents and Children U.K. birth cohort followed for up to 13 years.
The findings showed that total fat mass partly mediated the inverse associations of LPA (by 13 percent for low-density lipoprotein cholesterol, by 28 percent for triglyceride, and by 6 percent for total cholesterol). Inverse associations of MVPA with low-density lipoprotein cholesterol and total cholesterol were mediated by total fat mass by 37 and 48 percent, respectively, attenuating the effect on total cholesterol to nonsignificance. Higher MVPA at age 15 years was associated with lower low-density lipoprotein cholesterol at 24 years but not vice versa.
"Engaging in light physical activity for three to four hours/day may be an effective way to reduce high cholesterol and avoid heart health issues later in life," Agbaje said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted December 2023
Read this next
Semaglutide Cuts Risk for Kidney Outcomes, Death in CKD With T2DM
FRIDAY, May 31, 2024 -- For patients with type 2 diabetes and chronic kidney disease, semaglutide reduces the risk for clinically important kidney outcomes and death from...
DNA Methylation-Based Epigenetic Age Mediates Link Between LE8 Score, CVD
WEDNESDAY, May 29, 2024 -- The associations between Life's Essential 8 (LE8) and cardiovascular health are mediated by DNA methylation-based epigenetic age, according to a study...
Semaglutide Boosts Kidney Outcomes With Obesity + Cardiovascular Disease
TUESDAY, May 28, 2024 -- Once-weekly subcutaneous semaglutide shows a benefit for kidney outcomes in people with overweight or obesity and established cardiovascular disease...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.