Prostate MRI Has Independent Screening Value
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
WEDNESDAY, Aug. 23, 2023 -- Prostate magnetic resonance imaging (MRI) has a value for screening independent of prostate-specific antigen (PSA), according to a study published online Aug. 21 in BMJ Oncology.
Caroline M. Moore, M.D., from University College London, and colleagues reported a systematic community-based assessment of the prevalence of prostate MRI lesions among men aged 50 to 75 years. Men were identified from eight participating general practitioner practices and were randomly selected for invitation to a screening MRI and PSA. The U.K. Standard National Health Service (NHS) prostate cancer assessment was recommended for those with a positive MRI or elevated PSA density.
Invitations were sent to 2,096 men; 457 responded, and 303 completed both screening tests. The researchers found that older White men were most likely to respond to the invitation; the acceptance rate for Black men was 20 percent of that for White men. Sixteen percent of men had a positive screening MRI, and 5 percent had a raised PSA density alone. Overall, 9.6 percent of men were diagnosed with clinically significant cancer and 1 percent with clinically insignificant cancer after NHS assessment. Two-thirds of men with a positive MRI and more than half with clinically significant disease had a PSA <3 ng/mL.
"Given the incomplete overlap of the risk profiles generated by PSA and MRI, we would encourage each to be used in further research, to assess whether a stepwise approach can be adopted," the authors write.
Several authors disclosed ties to the biopharmaceutical and medical device industries.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted August 2023
Read this next
BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults
FRIDAY, May 31, 2024 -- The optimal body mass index (BMI) cutoff point appears to be 27 kg/m2 for detecting obesity in middle-aged and older adults, according to a study presented...
Emergency Inguinal Hernia Surgery Rates Increased With Lower Country Income
FRIDAY, May 31, 2024 -- For patients undergoing inguinal hernia surgery, emergency surgery rates increase from high- to low-income countries, according to a study published online...
Maternal Serum Alpha-Fetoprotein Levels Higher in Black Than White Women
FRIDAY, May 31, 2024 -- Maternal serum alpha-fetoprotein (AFP) levels are higher in Black than White pregnant women, supporting the use of accounting for these differences in...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.