Long-Term Risk for MACE Increased for Children With Hypertension
By Elana Gotkine HealthDay Reporter
TUESDAY, May 7, 2024 -- The long-term risk for major adverse cardiac events (MACE) is increased for children diagnosed with hypertension, according to a study published online May 6 in JAMA Pediatrics to coincide with the annual meeting of the Pediatric Academic Societies, held from May 2 to 6 in Toronto.
Cal H. Robinson, M.D., from The Hospital for Sick Children in Toronto, and colleagues examined the long-term associated risk for MACE among children with hypertension in a population-based, retrospective cohort study conducted from 1996 to 2022. Data were included for 25,605 children with hypertension compared with 128,025 controls without hypertension matched by age, sex, birth weight, maternal gestational hypertension, prior comorbidities, and a propensity score for hypertension.
The researchers found that the incidence of MACE was 4.6 and 2.2 per 1,000 person-years in children with hypertension and controls, respectively (hazard ratio, 2.1), during a median follow-up of 13.6 years. Higher associated risks for stroke, hospitalization for myocardial infarction or unstable angina, coronary intervention, and congestive heart failure were seen for children with hypertension, but there was no increase in risk seen for cardiovascular death.
"Optimizing the care provided to youth with hypertension may help prevent long-term adult cardiovascular disease, with substantial health and cost-saving benefits," the authors write.
Two authors disclosed ties to the biopharmaceutical industry.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted May 2024
Read this next
Prevalence of Cardiovascular Risk Factors, Diseases Set to Increase
THURSDAY, June 6, 2024 -- The prevalence of cardiovascular risk factors and diseases will increase through 2050, and the associated economic burden is also projected to increase...
Adherence to Mediterranean Diet Linked to Lower Risk for Mortality
TUESDAY, June 4, 2024 -- Adherence to the Mediterranean diet is associated with a lower risk for all-cause mortality, which is partly explained by multiple cardiometabolic...
Gastrectomy for Gastric Cancer Tied to Lower Risk for Cardiovascular Events
TUESDAY, June 4, 2024 -- Patients with gastric cancer who undergo gastrectomy have a lower risk for cardiovascular events than the general population, according to a study...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.