Graded Association ID'd for Depressive Symptoms With Mortality Risk
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
TUESDAY, Oct. 17, 2023 -- Depressive symptoms in adults are associated with mortality in a graded association, according to a study published online Oct. 9 in JAMA Network Open.
Zefeng Zhang, M.D., Ph.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues conducted a prospective cohort study to examine the association between depressive symptoms and mortality in a large, nationally representative sample of 23,694 U.S. adults.
The prevalence of mild depression was 14.9 percent, and prevalence of moderate-to-severe depression was 7.2 percent. The researchers found that the hazard ratios (with 95 percent confidence intervals) were 1.35 (1.07 to 1.72) and 1.62 (1.24 to 2.12) for all-cause mortality for mild and moderate-to-severe depressive symptoms versus none. The corresponding hazard ratios (95 percent confidence intervals) were 1.49 (1.11 to 2.00) and 1.79 (1.22 to 2.62) for cardiovascular disease (CVD) mortality and 0.96 (0.58 to 1.60) and 2.21 (1.24 to 3.91) for ischemic heart disease mortality. Across subgroups, the associations were largely consistent. Lifestyle factors explained about 11.0 to 16.1 percent of the associations between depression and mortality. Independent associations were seen for feeling tired or having little energy, poor appetite or overeating, and having little interest in doing things with all-cause and CVD mortality but not ischemic heart disease mortality.
"Taken together with the body of literature on associations between depression and CVD mortality, these findings can support public health efforts to develop a comprehensive, nationwide strategy to improve well-being, including both mental and cardiovascular health," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted October 2023
Read this next
Teens May Experience Delays in Bipolar Progression After Major Depressive Disorder
FRIDAY, May 31, 2024 -- Adolescents may experience delayed bipolar disorder (BD) progression after major depressive disorder (MDD) diagnosis, according to a study published online...
Teen Smartphone Use Positively Tied to Mood
THURSDAY, May 30, 2024 -- Adolescent smartphone use is positively associated with mood, according to a study published online May 29 in PLOS ONE. Matt Minich, Ph.D., and...
Changes in Gender Identity Not Tied to Depressive Symptoms in Youth
WEDNESDAY, May 29, 2024 -- Changes in gender identity are not associated with changes in depressive symptoms over time among sexual and gender minority (SGM) youth, according to a...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.