Factors ID’d That Increase Risk for Mechanical Ventilation With Sepsis
Medically reviewed by Drugs.com.
By Lori Solomon HealthDay Reporter
FRIDAY, Sept. 1, 2023 -- Certain factors may independently increase the risk for mechanical ventilation following a sepsis diagnosis, according to a study published online Sept. 1 in the American Journal of Critical Care.
Robert E. Freundlich, M.D., from Vanderbilt University Medical Center in Nashville, Tennessee, and colleagues used electronic health record data from 28,747 patients with sepsis to model risk factors for initiation of mechanical ventilation after the onset of sepsis.
The researchers found that mechanical ventilation was initiated within 30 days after sepsis onset in 13.5 percent of patients, with 52.6 percent requiring mechanical ventilation within 24 hours of diagnosis. Race (White: adjusted hazard ratio [aHR], 1.59; other/unknown: adjusted HR, 1.97), systemic inflammatory response syndrome (aHR [per point], 1.23), Sequential Organ Failure Assessment score (aHR [per point], 1.28), and congestive heart failure (aHR, 1.30) were independently associated with an increased likelihood of receipt of mechanical ventilation. Risk varied with time after sepsis onset and by comorbidities.
“Through a better understanding of risk factors for initiation of mechanical ventilation in patients with sepsis, targeted interventions may be tailored to high-risk patients,” the authors write.
Freundlich reports ties to Medtronic, a medical device company.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted September 2023
Read this next
BMI Cutoff of 30 for Obesity May Be Too High for Middle-Aged, Older Adults
FRIDAY, May 31, 2024 -- The optimal body mass index (BMI) cutoff point appears to be 27 kg/m2 for detecting obesity in middle-aged and older adults, according to a study presented...
Emergency Inguinal Hernia Surgery Rates Increased With Lower Country Income
FRIDAY, May 31, 2024 -- For patients undergoing inguinal hernia surgery, emergency surgery rates increase from high- to low-income countries, according to a study published online...
Maternal Serum Alpha-Fetoprotein Levels Higher in Black Than White Women
FRIDAY, May 31, 2024 -- Maternal serum alpha-fetoprotein (AFP) levels are higher in Black than White pregnant women, supporting the use of accounting for these differences in...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.