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How long does it take for Strattera to work?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on May 1, 2024.

Official answer

by Drugs.com

Strattera starts to work for attention-deficit hyperactivity disorder (ADHD) as soon as the first day of taking a dose. However, it can take 8-12 weeks for its full effects to be reached. Some people may continue to notice an increased response for up to 24 weeks or longer.

The time it takes for Strattera to work can depend on your dosing schedule. The dose is usually started low and then raised up to a maintenance dose over days to weeks. Strattera doesn’t work for everyone. If your ADHD symptoms don’t improve within 6 to 8 weeks, your doctor may consider other treatment options.

How is Strattera dosed?

In children and teens who weigh up to 70 kg, the usual starting dose of Strattera is 0.5 mg/kg by mouth per day. After a few days, the dose is increased to 1.2 mg/kg per day. The maximum recommended dose is 1.4 mg/kg per day or 100 mg (whichever is less).

In people over 70 kg, the usual starting dose is 40 mg by mouth per day. After a few days, the dose is increased to 80 mg per day. The dose can be increased again after 2-4 weeks, up to 100 mg.

If you have liver problems or are taking certain medications that interact with Strattera, your prescriber may recommend a different dose.

Strattera can be taken as a single dose in the morning, or as two equal doses (in the morning and late afternoon or early evening).

References

Clemow, D. B., et. al. (2015). Atomoxetine in patients with ADHD: A clinical and pharmacological review of the onset, trajectory, duration of response and implications for patients. Journal of Psychopharmacology. Available at: https://pubmed.ncbi.nlm.nih.gov/26349559/ [Accessed May 1, 2024].

Stahl, S. M. Atomoxetine. Prescriber’s Guide. October 2021. Available at: https://www.cambridge.org/core/books/abs/prescribers-guide/atomoxetine/2F95EF4C484E4091A28E3489ECBDF251 [Accessed May 1, 2024].

Strattera [Package Insert]. Revised 01/2022. Eli Lilly and Company - https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=309de576-c318-404a-bc15-660c2b1876fb

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