Promethazine Injection Shortage

• • Phenergan injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-6082-25
  • Phenergan injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-6083-25
  • Promethazine injection, Hikma, 50 mg/mL, 1 mL ampule, 25 count, NDC 00641-1496-35

• • Hikma has promethazine injection on shortage due to increased demand.
  • X-Gen has promethazine injection available.

• • Phenergan injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-6084-25
  • Phenergan injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-6085-25
  • Promethazine injection, Hikma, 25 mg/mL, 1 mL ampule, 25 count, NDC 00641-1495-35
  • Promethazine injection, Hikma, 25 mg/mL, 1 mL vial, 25 count, NDC 00641-0928-25
  • Promethazine injection, Hikma, 50 mg/mL, 1 mL vial, 25 count, NDC 00641-0929-25
  • Promethazine injection, X-Gen, 25 mg/mL, 1 mL ampule, 25 count, NDC 39822-5525-03
  • Promethazine injection, X-Gen, 50 mg/mL, 1 mL ampule, 25 count, NDC 39822-5550-06

Estimated Resupply Dates

• • Hikma has promethazine 50 mg/mL 1 mL ampules on back order and the company estimates a release date of early-May 2024.
  • Hikma has Phenergan 25 mg/mL 1 mL ampules on back order and the company estimates a release date of mid-May 2024. The 50 mg/mL 1 mL ampules are on back order and the company cannot estimate a release date.

Safety

• • ISMP has a list of recommendations in the 2018-2019 Targeted Medication Safety Best Practices for Hospitals including the removal of promethazine from hospitals. Detailed information can be found at https://www.ismp.org/sites/default/files/attachments/2019-01/TMSBP-for-Hospitalsv2.pdf.