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Glucagon Injection Shortage

Last Updated: February 28, 2024
Status: Current

Products Affected - Description
    • GlucaGen Hypokit lyophilized powder for injection, Novo Nordisk, 1 mg, 1 mL vial with 1 mL syringe of Sterile Water for Injection kit, NDC 00169-7065-15
Reason for the Shortage
    • Amphastar has glucagon 1 mg emergency kits available.
    • Boehringer Ingelheim discontinued GlucaGen vials. The company discontinued GlucaGen diagnostic kits in September 2022.
    • Fresenius Kabi has glucagon available.
    • Lilly discontinued glucagon 1 mg emergency kits. Baqsimi intranasal devices will continue to be available.
    • Novo Nordisk has made the decision to discontinue GlucaGen Hypokits in the US market and concentrate on its use in areas of the world where there is limited access to glucagon. The company expects product to not be orderable in mid-2024.
    • Xeris Pharmaceuticals discontinued Gvoke prefilled syringes 0.5 mg/0.1 mL in January 2023. Gvoke Hypopen (2 pack) will continue to be available for pediatric patients. All other Gvoke products will continue to be available.
Available Products
    • Gvoke Hypopen subcutaneous solution for injection, Xeris Pharmaceuticals, 0.5 mg/0.1 mL, auto-injector, 2 count, NDC 72065-0120-12
    • Gvoke Hypopen subcutaneous solution for injection, Xeris Pharmaceuticals, 1 mg/0.2 mL, auto-injector, 2 count, NDC 72065-0121-12
    • Gvoke Kit subcutaneous solution for injection, Xeris Pharmaceuticals, 1 mg/0.2 mL, vial and syringe kit, NDC 72065-0140-11
    • Gvoke PFS subcutaneous solution for injection, Xeris Pharmaceuticals, 1 mg/0.2 mL, prefilled syringe, 2 count, NDC 72065-0131-12
    • Gvoke PFS subcutaneous solution for injection, Xeris Pharmaceuticals, 1 mg/0.2 mL, prefilled syringe, NDC 72065-0131-11
    • Glucagon lyophilized powder for injection, Amphastar, 1 mg Emergency Kit, with 1 mL of diluent in a prefilled syringe kit, NDC 00548-5850-00
    • Glucagon lyophilized powder for injection, Fresenius Kabi, 1 mg, 1 mL single dose vial, 10 count, NDC 63323-0596-13
    • Glucagon lyophilized powder for injection, Fresenius Kabi, 1 mg Diagnostic Kit, 1 mL vial with 1 mL vial of Sterile Water for Injection kit, NDC 63323-0593-03
    • Glucagon lyophilized powder for injection, Fresenius Kabi, 1 mg Emergency Kit, with 1 mL of diluent in a prefilled syringe kit, NDC 63323-0582-82

Estimated Resupply Dates

    • NovoNordisk is discontinuing 1 mg GlucaGen Hypokit in mid-2024.

Updated

Updated February 28, 2024 by Michelle Wheeler, PharmD, Drug Information Specialist. Created October 18, 2022 by Leslie Jensen, PharmD, Drug Information Specialist. © 2024, Drug Information Service, University of Utah, Salt Lake City, UT.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.